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No, it’s not safe to take an 80-mg dose of Cialis. The utmost recommended day by day dosage of Cialis is twenty mg every day if you take it as desired for ED. If you are taking Cialis day-to-day, the most dosage is 5 mg a day.Alcuni gruppi di pazienti con malattia cardiovascolare non sono stati inclusi negli studi clinici con tadalafil; pertanto,